![]() ![]() ![]() Enveloped virus inactivation on personal protective equipment by exposure to ozone. Ambient ozone and influenza transmissibility in Hong Kong. These data can be used for reducing significantly the viral load although for assuring a safe disinfection, the effective dosages under different conditions need to be confirmed with experimental data.ĬOVID-19 Coronavirus Disinfections Heat & liquid sensitive materials Ozone gas SARS-CoV-2.Īli ST, Wu P, Cauchemez S, He D, Fang VJ, Cowling BJ, Tian L. At these ozone levels, safety protocols must be strictly followed. Maximum antiviral activity of ozone is achieved at high humidity, while the same ozone concentrations under low RH could result inefficient. In large rooms, 30 to 50 mg ozone/m 3 would be required for treatments of 20-30 min. In small chambers, 10-20 mg ozone/m 3 over 10 to 50 min can be sufficient to significantly reduce the virus load of personal protection equipment. Based on these data, conservative dosages and times to inactivate the SARS-CoV-2 are estimated. The data have been classified depending on the disinfection objective and the volume and type of the experimental set-up. Published papers have been critically analyzed to evaluate trends in the required ozone dosages, as a function of relative humidity (RH), contact time, and viral strains. The review covers disinfection treatments of both air and surfaces carried out in different volumes, which varies from small boxes and controlled chambers to larger rooms, as a base to develop future ozone protocols against COVID-19. This paper reviews the most relevant results of virus disinfection by the application of gaseous ozone. As of this writing, evidences are still accumulating for the use of ozone gas as a disinfectant for sanitary materials and ambient disinfection in indoor areas. However, heat and liquid treatments can damage some materials, and ultraviolet light is not efficient in shaded areas, so other disinfection alternatives are required to allow safe re-utilization of materials and spaces. Although it is quite infectious, the SARS-CoV-2 virus itself is an enveloped virus that is relatively fragile because its protective fatty layer is sensitive to heat, ultraviolet radiation, and certain chemicals. Until a vaccine is available, personal protection, social distancing, and disinfection are the main tools against SARS-CoV-2. The greatest challenge the world is facing today is to win the battle against COVID-19 pandemic as soon as possible. ![]()
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